High accuracy template based modeling by global optimization
نویسندگان
چکیده
منابع مشابه
High accuracy template based modeling by global optimization.
For high-accuracy template-based-modeling of CASP7 targets, we have applied a procedure based on the rigorous optimization of score functions at three stages: multiple alignment, chain building, and side-chain modeling. We applied the conformational space annealing method to a newly developed consistency based score function for multiple alignment. For chain building, we optimized the MODELLER ...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2007
ISSN: 0887-3585,1097-0134
DOI: 10.1002/prot.21628